| | National Framework Apprenticeship Training & End Point Assessment, Tranche 1 March | Salisbury | £1T |
| | Medical Examination Gloves and Surgical Gloves | London | £6B |
| | Clinical Digital Solutions (CDS) for the Integrated Health Economy Framework | London | £5B |
| | Single Use PPE and Medical Protective Consumables | London | £5B |
| | Contact Centres and Business Services | Liverpool | £4B |
| | North West Contractor Framework | Oldham | £2B |
| | Passenger Service Technical Advisors | London | £2B |
| | Software Design and Implementation Services | Liverpool | £2B |
| | Software Design & Implementation Services | Liverpool | £2B |
| | Voucher Schemes | Liverpool | £2B |
| | SARS-CoV-2 Antigen Rapid Qualitative Tests (Self-Tests) | London | £1B |
| | AASC - Asylum Accommodation & Support Services NW | London | £1B |
| | AASC - Asylum Accommodation & Support Services MEE | London | £1B |
| | Care in a Residential Setting With or Without Nursing (IRN) | Chelmsford | £1B |
| | National Framework Apprenticeship Training & End Point Assessment, Tranche 1 March | Salisbury | £1B |
| | This Is a Notice for Social and Specific Services in Accordance With Directive 2014/24/EU Article 74… | Chelmsford | £1B |
| | AASC - Asylum Accommodation & Support Services NEYH | London | £821M |
| | AASC - Asylum Accommodation & Support Services South | London | £662M |
| | Cutting Edge for the Appointment of Contractors Relating to the Development and Improvement of Housing Stock… | Liverpool | £625M |
| | Risk Assessments Framework Procurement | Birmingham | £600M |
| | Transportation: Patient and Specialist Courier Services | Cambridge | £600M |
| | JV North Contractors Framework | Northwich | £540M |
| | AASC - Asylum Accommodation & Support Services Scotland | London | £514M |
| | B2G Minor Works — England | Chalfont St Peter | £500M |
| | AASC - Asylum Accommodation & Support Services Wales | London | £334M |
| | Home Support Framework for Norfolk | Norwich | £300M |
| | Risk Assessments Framework Procurement | Birmingham | £300M |
| | Drugs of Abuse and Wider Point of Care Testing | Salford | £280M |
| | Residential and Nursing Care Home Services | Stafford | £275M |
| | South East Consortium New Build Framework | Surrey | £250M |
| | Community Home Care Service | Leeds | £201M |
| | Learning Disability Community Support Services | Leeds | £165M |
| | Skills Framework | Stockton on Tees | £160M |
| | BEIS Heat Networks Investment Vehicle (BHIVE) | London | £150M |
| | Fares Reform Tech Advisors | London | £150M |
| | Homes England - First Homes Pilot | London | £150M |
| | Occupational Health, Employee Assistance Programmes and Eye Care | Liverpool | £143M |
| | CSKL & TPPL Vehicle Rental Framework | West Malling | £120M |
| | AASC - Asylum Accommodation & Support Services NI | London | £113M |
| | Modular Housing Framework | Lewes | £110M |
| | Network Rail Telecoms - Professional Services to Deliver Project and Programmes Outcomes | London | £100M |
| | South East Consortium New Build Framework | Surrey | £100M |
| | Cardiovascular & Respiratory Medicines | Edinburgh | £96M |
| | Compute (OGVA) | London | £94M |
| | Provider Panel for Day Service | Durham | £90M |
| | Provider Panel for Day Services | Durham | £90M |
| | CHIC Consultancy Services Framework | Birmingham | £88M |
| | General Office Supplies | Edinburgh | £80M |
| | National Education Printer Agreement 2 (Nepa 2) | Leeds | £80M |
| | Roundless Tactical Engagement Simulation (RTES) | Bristol | £79M |
| | Catering (Food/Drink/Technology/Equipment) Innovation and Concept Solutions | Manchester | £75M |
| | Engineering and Technical Consultancy | Paisley | £72M |
| | Medical Healthcare Furniture | Sheffield | £64M |
| | Facilities Management | Truro | £60M |
| | Select List Framework for Highway Works | Lincoln | £60M |
| | Transportation: Patients and Specialist Courier Services | Cambridge | £60M |
| | Sexual Health and Reproductive Services | Liverpool | £51M |
| | Electrical Vehicle Charging Point - Supply, Installation, Maintenance and Consultancy | Salford | £50M |
| | Framework for Dangerous Structures | London | £50M |
| | Emergency Response Equipment and Associated Services | Birmingham | £45M |
| | IT Services: Consulting, Software Development, Internet and Support | London | £42M |
| | Heart of the City II - Block H | Sheffield | £42M |
| | Waltham Forest Home Based Support Service - Market Engagement | London | £42M |
| | Office Supplies | Liverpool | £40M |
| | RFI NHSE Covid-19 Vaccination Programme Distribution | Derby | £40M |
| | Gastro Intestinal, Endocrine, Nutrition & Blood Generic Medicines | Edinburgh | £37M |
| | Structural Integrity - Southern Region | London | £36M |
| | Breast Screening Programme in Surrey and North East Hampshire | Southampton | £35M |
| | Office & Business Solutions Framework Agreement | Warrington | £35M |
| | Speech and Language Therapy Service | Norwich | £34M |
| | Skin Cleansing Disinfection and Care | Normanton | £32M |
| | Marketing Services - (2022 | Edinburgh | £30M |
| | Online Training in Project Management Skills — DPS for Skills Providers and Training Provision, Skills for… | Chester | £27M |
| | Port Infrastructure Partner | Liverpool | £26M |
| | Collection of Plasma for Fractionation | Bristol | £26M |
| | NRW Civil Engineering - (CEFA) Phase 2 | Cardiff | £26M |
| | Stopped Vehicle Detection (SVD) 2020 (Lot 1) | Birmingham | £26M |
| | Access to Argyll and Bute (A83) | Glasgow | £25M |
| | Land, Design and Build Greater Belfast | Belfast | £25M |
| | Clean Air Zone Technical Delivery and Support Provider | London | £22M |
| | Community Dental Services | Durham | £22M |
| | CIPHA- Combined Intelligence for Population Health Action | Prescot | £22M |
| | JV North Consultants Framework | Norwich | £20M |
| | Short Breaks Support Service for Children, Young People & Families | Manchester | £20M |
| | General Building Works 3 | Hackney | £20M |
| | New Build Construction for a Pathology Building at the Royal Bournemouth Hospital, Bournemouth, Dorset | Bournemouth | £20M |
| | Integrated Domestic Abuse and Substance Misuse Model (IDAS) - Procuring a Delivery Partner | Redcar | £19M |
| | NHS National Pharmaceuticals - Everolimus and Terminated Agreement Products | Runcorn | £19M |
| | Vehicle Lease, Fleet Management and Flexible Rental Solutions | Salford | £18M |
| | Strategic Implementation Partner for the Implementation of Organisational Design at BCP Council | Bournemouth | £18M |
| | Auto-Injector Partner | Bristol | £18M |
| | Construction Framework Delivery and Management Partner | Oldham | £16M |
| | Fleming Way Bus Boulevard - Market Engagement Event | Swindon | £16M |
| | Fleming Way Bus Boulevard - Prior Information Notice | Swindon | £16M |
| | Security Equipment | Birmingham | £16M |
| | Alternative Education | Walsall | £16M |
| | Termination of Pregnancy Services (Sussex) CAN | Lewes | £15M |
| | British National Formulary | London | £15M |
| | Local Bus and Shared Taxi & Demand Responsive Services DPS | Milton Keynes | £15M |
| | Main Part Steel & Circular Hollow Material FW for Railway Overhead Line Electrification | Pontypridd | £15M |