| | Care in a Residential Setting With or Without Nursing (IRN) | Chelmsford | £10B |
| | Waste Management Services | London | £8B |
| | Establishment of a Joint Venture Development Company | Nelson | £2B |
| | Grant of Offshore Transmission Licence for the Hornsea One Project | London | £1B |
| | Support and Accommodation Framework for People With a Learning Disability, Mental Health Problem, Autism or a… | Carlisle | £1B |
| | Personal Independence Payments (PIP) Assessment Service Extension — Lot 1 | Leeds | £873M |
| | Managed Equipment & Clinical Service Solutions | London | £860M |
| | COVID Infection Survey (CIS)Services Related to COVID-19 - CIS Prime Provider | Gwent | £710M |
| | Personal Independence Payments (PIP) Assessment Service Extension - Lot 3 | Sheffield | £706M |
| | Town and Country Housing Group - Housing Maintenance Joint Venture | Tunbridge Wells | £700M |
| | Town and Country Housing - Housing Maintenance Joint Venture | Tunbridge Wells | £700M |
| | Domestic Retrofit Measures | London | £608M |
| | Personal Independence Payments (PIP) Assessment Service Extension - Lot 2 | Sheffield | £558M |
| | Home Care Including Carers Home Based Respite Services in Staffordshire | Stafford | £506M |
| | T-CE Construction Framework | Chicksands | £500M |
| | Surface Technology Retender (STCR) | London | £389M |
| | Supported Living Framework Re-Opening August | Chichester | £360M |
| | Buckinghamshire Highways Term Maintenance Services | Aylesbury | £300M |
| | Go Neutral Smart Energy Framework | Salford | £300M |
| | Services-Framework-Pan-UU (United Utilities) Platform for Monitoring & Control, Analytics, Visualisation and Optimisation | Warrington | £270M |
| | Buckinghamshire Highways Term Maintenance Services | Aylesbury | £250M |
| | Software and Software Support Framework | Glasgow | £250M |
| | Specialist Materials (EWNI) Dynamic Purchasing System | Warrington | £250M |
| | Gloucestershire Health and Social Care Pseudo-Framework 2020 | Gloucester | £244M |
| | Biological Sample Processing, Genotyping, and Storage | Manchester | £212M |
| | Establishment of a Joint Venture Development Company | Nelson | £200M |
| | Home Care Including Carers Home Based Respite Services in Staffordshire | Stafford | £200M |
| | Surface Transport Infrastructure Construction Framework | London | £200M |
| | North Northamptonshire Council and West Northamptonshire Council - Tier 2 Home Care Services | Northampton | £180M |
| | Hyde Park Winter Wonderland 2018/19 – 2023/24 | London | £173M |
| | Hyde Park Winter Wonderland 2018/2019 – 2023/24 | London | £173M |
| | Motor Control Centre and Systems Integration | Glasgow | £160M |
| | Homes England - First Homes Early Delivery Programme 2021-23 | Coventry | £150M |
| | Homes England - First Homes Pilot | Newcastle | £150M |
| | Passive Investment Management Services | Norwich | £140M |
| | Development Management Partner | Huyton | £128M |
| | Carmarthen Gamma Lab | London | £127M |
| | Test Samples and Supporting Materials | London | £122M |
| | Repair and Maintenance of Large Engines, Transmissions and Terrier Assemblies | Telford | £121M |
| | Fostering and Continuing Care Services | Paisley | £106M |
| | Sovereign Housing Association Materials Supply via NEPO219 DPS | Basingstoke | £100M |
| | DRW Samba II Reagent | London | £96M |
| | DRW Samba II Reagent | London | £96M |
| | TSP Phase 2 Digital Apps CMDG Pega | London | £90M |
| | Sexual Health Services and HIV Services in Staffordshire, Stoke on Trent, and Telford and Wrekin | Stafford | £86M |
| | Furniture | Durham | £85M |
| | Natural Gas | Cardiff | £83M |
| | eMarketplace to Facilitate Tailend Spend | Leeds | £80M |
| | Integrated Urgent Care Services on Behalf of the South West London Integrated Care System | London | £80M |
| | Rail Legal Services | Liverpool | £80M |
| | Rail Legal Services Framework | Liverpool | £80M |
| | Homecare Medicines Services | Fulbourn | £75M |
| | Progress Housing Group Repairs and Voids | Leyland | £75M |
| | Progress Housing Group Repairs and Voids | Leyland | £71M |
| | 16+ Services - Young People Supported Accommodation and Tenancy Support | Nottingham | £68M |
| | Managed Service for Temporary Agency Workers | London | £66M |
| | Staffordshire and Stoke on Trent GP Out of Hours Service | Stoke on Trent | £65M |
| | NEPO411 Furniture | Durham | £65M |
| | Civil Service Central Apprenticeship | London | £63M |
| | Electrical Consumables and Associated Items | Telford | £60M |
| | Motion Control Spares and Repairs | Bristol | £60M |
| | Vehicle Conversions Framework | Lewes | £60M |
| | Refurbishment of B329/330 | London | £59M |
| | Building Fabric, Mechanical & Electrical Maintenance Services | Liverpool | £58M |
| | Electrical Vehicle Charging Point - Supply, Installation, Maintenance and Consultancy | Salford | £50M |
| | Single Non-Emergency Number | London | £50M |
| | Single Non-Emergency Number (SNEN) | Westminster London | £50M |
| | HCTVP ICT VAR for Software, Associated Support and Maintenance | Kidlington | £48M |
| | Thermometer Devices and Support Products | Normanton | £48M |
| | City of York Council - Housing Development Programme - Burnholme and Duncombe Barracks | York | £48M |
| | Highway Maintenance and Civil Engineering Works | Enfield | £45M |
| | Property Services - Fire - 12 Fire Remedials and Fire Equipment Service & Maintenance | London | £43M |
| | Integrated Community Equipment Loans Service | Leicester | £42M |
| | Medical Gases | Fulbourn | £40M |
| | MRI Scanners and Associated Partnership: Gray’s Inn Road Neuroscience Centre | London | £40M |
| | MRI Scanners & Associated Partnership: Gray's Inn Road Neuroscience | London | £40M |
| | PfH Decorative Solutions & Associated Services Framework | Warrington | £40M |
| | Technical and Highways Works Framework | Swinton | £40M |
| | Transition Management and Implementation Services | Norwich | £40M |
| | Thermometer Devices and Support Products | London | £37M |
| | NHS Education With Royal Berkshire Hospitals NHS Foundation Trust | Leeds | £35M |
| | NHS Education Royal Berkshire Hospitals NHS Foundation Trust | Leeds | £35M |
| | Sunderland Eye Infimary | Sunderland | £34M |
| | Bespoke Care Package for a Young Person in Peterborough | Peterborough | £34M |
| | Red Kite Community Housing Planned Works Framework | High Wycombe | £33M |
| | Surrey Healthy Children and Families Limited Liability Partnership for a Surrey Children's Community Health Service | Leatherhead | £33M |
| | B358 Cattle Handling System | London | £32M |
| | 16+ High Support Needs Accommodation Open Framework | Winchester | £30M |
| | Cirrus Consortium Kitchen Supply Framework | Widnes | £30M |
| | Learning Disabilities & Autism Supported Living Care Provision | Winchester | £30M |
| | BASS - Extension of to 30 September | London | £29M |
| | Network Access Services (NAS) Circuit Bandwidth Capacity Increases | Blackpool | £29M |
| | Growth Gateway | East Kilbride | £28M |
| | FE (Further Education) Colleges Sector Framework for Planned Preventative Maintenance, Response Maintenance and Minor Works | Belfast | £28M |
| | Lot-2-Call-Off Teleperformance Call Off | Leeds | £28M |
| | Grocery, Soft Drinks and Frozen Food Products to Lancashire County Council | Preston | £27M |
| | Franking Machines & Consumables | Stirling | £24M |
| | PHE Porton FM Hard Services | Salisbury | £22M |
| | Property Services - M&E - 11 | London | £21M |
| | B265 Functional Safety Alignment | London | £21M |