| | Offsite Construction Solutions | Liverpool | £10B |
| | Southern Integrated Delivery (SID) – Signalling and Track | London | £10B |
| | SCF Residential Delivery and Development Framework | Exeter | £5B |
| | Digital Document Solutions | London | £5B |
| | Healthcare Services by NHS and Other Public Bodies (Including Clinical Services) | Sheffield | £2B |
| | Demand Management & Renewables | Liverpool | £1B |
| | Demand Management & Renewables - DPS | Liverpool | £1B |
| | Demand Management & Renewables (HELGA 2) | Liverpool | £1B |
| | Demand Management & Renewables (HELGA 2) DPS | Liverpool | £1B |
| | Strategic HR Services | Leicester | £1B |
| | Publication of Redacted Contracts | Sheffield | £873M |
| | Energy to Catholic Education Establishments in England & Wales | Cannock | £800M |
| | Publication of Redacted Contracts | Sheffield | £706M |
| | Managed Equipment & Clinical Service Solutions | London | £642M |
| | Civil Engineering Works and Associated Services (Including Roads and Roads Maintenance) - New PIN Notice | Edinburgh | £600M |
| | Publication of Redacted Contracts | Sheffield | £558M |
| | Low Value Facilities Management & Workplace Services DPS | Liverpool | £500M |
| | Managed Services | West Malling | £500M |
| | Multi-Functional Devices and Digital Solutions | West Malling | £500M |
| | Legal Services Framework | Liverpool | £430M |
| | Cornwall Council and NHS Kernow Care Home | St Austell | £355M |
| | Waste and Environmental Services | Milton Keynes | £300M |
| | Accommodation With Care | Town | £270M |
| | Domiciliary and Personal Care Services | London | £258M |
| | Home Group - Northern Home Counties Repairs, Maintenance and Compliance | Newcastle upon Tyne | £250M |
| | Managed Solution Framework | London | £230M |
| | Estates Management Professional Services | Leicester | £160M |
| | NHS England and NHS Improvement South East - Integrated Healthcare Services to Kent and Medway Prisons… | Bristol | £150M |
| | Core Banking, Payment and Reporting | London | £141M |
| | SDF Lot 3.1 South_ H W Martin (Traffic Management) LTD A | Birmingham | £140M |
| | Customer Contact and Operations | London | £129M |
| | SDF Lot 3.1 C_ Chevron Traffic Management Limited A | Birmingham | £116M |
| | NHS England and NHS Improvement South East - Integrated Healthcare Services to Kent and Medway Prisons… | Surrey | £110M |
| | 3 Thames Road Newham - Residential Agreement for Lease | London | £105M |
| | Capital Turnkey Solutions and Community Diagnostic Centres Dynamic Purchasing System | Chester | £100M |
| | Security Services | Leicester | £100M |
| | Integrator Change Request ICR255 | Leeds | £99M |
| | Generic Identity Verification (GIDV) | London | £91M |
| | Affordable Financial Services Products: No Interest Loan Scheme (NILS) and Other Innovative Affordable Finance Solutions | London | £90M |
| | MoJ: Estates Delivery Partner: Multi Disciplinary Services | London | £90M |
| | Nutritional Products, Devices, Consumables and Associated Services [3960617] | Belfast | £90M |
| | Sexual Health Services and HIV Services in Staffordshire, Stoke on Trent, and Telford and Wrekin | Stafford | £86M |
| | SDF Lot 3.1 S_ Chevron Traffic Management Limited B | Birmingham | £84M |
| | SDF Lot 3.1 South_ Chevron Traffic Management Limited B | Birmingham | £84M |
| | Integrated Sexual Health & HIV Services in Staffordshire, Stoke on Trent and Telford & Wrekin | Stafford | £83M |
| | Microbiology Serology Testing | Bristol | £80M |
| | Surfacing Works for Gloucestershire County Council 2022 to 2024(26) | Gloucester | £80M |
| | SDF Lot 3.1 North_ H W Martin (Traffic Management) LTD B | Birmingham | £72M |
| | Catering Equipment | Leicester | £70M |
| | SDF Lot 1.1 North_ Galliford Try Construction Limited B | Birmingham | £70M |
| | Children’s Residential Care, Fostering and Therapeutic Education Service | Taunton | £60M |
| | Retrofit Works (Housing Investment and Regeneration Programmes) | Paisley | £60M |
| | Specialist Vehicle Hire/Leasing | Leicester | £60M |
| | Innovation - Samba COVID19 Testing Equipment and Consumables | London | £60M |
| | Winter Surge Capacity (2021/22) | London | £58M |
| | Radiology Informatics System Procurement ("RISP") | Cardiff | £56M |
| | Employee Support Services and Benefits | West Malling | £50M |
| | Gas & Other Fuels Heating System Servicing, Maintenance Repair and Selected Replacement and Associated Services and… | Yeovil | £50M |
| | Framework for Beds, Mattresses and Wheelchairs Both Services and Products, Continence Home Delivery Services Plus Managed… | Hertfordshire | £49M |
| | DHSC: WTD - Information Management Services 4 (IMS4) | London | £49M |
| | Traffic Scotland Operations and Infrastructure Services | Glasgow | £48M |
| | Her Majesty's Prison's (HMP) Hull and Humber Primary Care Services | Leeds | £47M |
| | NERC Vessels Maintenance Framework | Swindon | £45M |
| | Educational Services Procured Services Arrangement (PSA) | Hamilton | £42M |
| | SDF Lot 2 Midlands_ Galliford Try Construction Limited | Birmingham | £41M |
| | SDF Lot 2 Midlands_ Galliford Try Construction Limited A | Birmingham | £41M |
| | Highways Professional Services Framework | Liverpool | £40M |
| | Multi-Supplier for Roads Based Transportation Multi-Disciplinary Consultancy Services: 2021 | Glasgow | £40M |
| | Water Lead Service Pipe Replacement | Coventry | £40M |
| | SDF Lot 3.2 South East_ Kier Highways Limited A | Birmingham | £37M |
| | HMPO Digital Future Services - Platforms | London | £37M |
| | NPS Media Buying, Integrated Marketing Campaigns and Public Relations Services Framework | Caerphilly | £35M |
| | COV - Property Asset Management Framework 2020 | Coventry | £34M |
| | Ground Preparation and Mechanised Establishment Operations | Inverness | £32M |
| | Northern Ireland Fire and Rescue Service - Learning and Development Centre, Cookstown | Belfast | £32M |
| | Mental Health Services for HMP Hull & HMP Humber | Leeds | £31M |
| | Framework for Beds, Mattresses and Wheelchairs Both Services and Products, Continence Home Delivery Services Plus Managed… | Hertfordshire | £29M |
| | Specialist Building Materials | Alfreton | £25M |
| | SDF Lot 4.1 South_ Forest Traffic Services Limited A | Birmingham | £25M |
| | Cymru Wales Destination Digital Marketing | Cardiff | £24M |
| | 23938004.08 | Bristol | £24M |
| | Private Sector Beds | Cardiff | £23M |
| | NOE CPC Medical Cylinder Gases | Sheffield | £22M |
| | Innovation - Samba COVID19 Testing Equipment and Consumables | London | £21M |
| | Supported Transport Dynamic Purchasing Solution (DPS) | Oxford | £21M |
| | Environmental and Conventional Health & Safety Services | Seascale | £20M |
| | Refuse Supplies Framework | Braintree | £20M |
| | Heathlands Dementia Nursing Care and Hotel Services | Bracknell | £18M |
| | Cheque Pouch Collection and Delivery Service | London | £18M |
| | Intermediate Tier Discharge to Assess (D2a) Patients Bed Facility Healthcare Services on Behalf of NHS Stockport… | Stockport | £18M |
| | Intermediate Tier Discharge to Assess (D2A) Patients Bed Facility Healthcare Services on Behalf of NHS Stockport… | Stockport | £18M |
| | House of Lords and Royal Gallery Cast Iron Roof Overhaul | London | £18M |
| | Greater Manchester Integrated Police Custody Healthcare and Wider Liaison and Diversion Service | Manchester | £17M |
| | RMBC -MB- An Expression of Interest in a Market Engagement Event in Connection With a Repairs,… | Addlestone | £16M |
| | Education Research in Conflict and Protracted Crisis (ERICC) | East Kilbride | £16M |
| | Competitive Land, Design and Build Framework NIHE South Region | Portadown | £15M |
| | Emergency and Out of Hours Work for Security and Safety Equipment | Worcester | £15M |
| | Home Care and Day Care Provision | Barking | £15M |
| | Overbridge at Eastern Green 2 | Coventry | £15M |
| | Soft Facilities Management Services | Liverpool | £15M |