| | Telecommunications Service for the Emergency Services of England, Scotland and Wales | London | £2B |
| | Deep Tube Upgrade Programme | London | £1B |
| | South East & Mid Wales Collaborative Construction Framework (SEWSCAP) | Cardiff | £1B |
| | Legal Services Framework | London | £772M |
| | Tender Round 9 (TR9) for the Grant of One Offshore Transmission Licence | London | £633M |
| | National Desktop and Notebook Agreement (NDNA) | London | £600M |
| | NHS National Generic Pharmaceuticals Wave 13 | Runcorn | £470M |
| | Electricity and Natural Gas | Warrington | £400M |
| | Lateral Flow Testing Devices for the Detection of COVID-19 Viral Antigens | London | £322M |
| | Boats/0007 - Maritime Overseer Support (MOS) for Boats and RFA | Bristol | £306M |
| | AHCSP/0005: Long Term Training and Support Service for Apache AH-64E Air System | Bristol | £286M |
| | Electronic Warfare Countermeasures Increment 1a | Bristol | £250M |
| | Angiography & Hybrid Theatre Equipment and Related Services | Warrington | £200M |
| | Technology and Associated Services | Hengoed | £200M |
| | Peritoneal Dialysis | Edinburgh | £155M |
| | Building Safety Contractor Framework | London | £153M |
| | Building Safety Improvement Works - Contractor Framework - Sprinklers, Alarms, Passive Fire | London | £153M |
| | Call for Competition: Wave 3 Skills Bootcamps Procurement Consisting of 7 Defined Lots | London | £150M |
| | MDCS - Winter Capacity (21/22) | London | £128M |
| | Design and Construction of the TIC East and West Buildings | Glasgow | £105M |
| | Lot 1 of the Deal 2030 Care and Support Ethical Framework) - Ethical Home Care | Wigan | £105M |
| | Design, Demonstration, Manufacture, Delivery and Installation & Commissioning and in Service Support of Maritime Electronic Warfare… | Bristol | £103M |
| | Homes England Property and Financial Professional Services Framework 2022 | Coventry | £100M |
| | Lancaster South Growth Catalyst Highway Infrastructure Early Supplier Involvement | Preston | £100M |
| | LB Havering Complex Placements Framework - Round 20 | Romford | £100M |
| | LPS CAS - Lancaster South Growth Catalyst Highway Infrastructure Early Supplier Involvement | Preston | £100M |
| | Supported Living Services for Individuals With a Learning Disability, Autistic Spectrum Conditions and/or Mental Health Conditions… | Stafford | £94M |
| | CSW - Refresh 2 - Care at Home Services Lots 2, 3 and 4 | Stratford | £91M |
| | Facilities Management | Truro | £90M |
| | Gigabit Infrastructure Subsidy Programme - Regional Supplier North East | London | £90M |
| | Gigabit Infrastructure Subsidy Programme Regional Supplier North East | London | £90M |
| | SDF Lot 1.1 South_ MJ Church (Plant) LTD B | Birmingham | £87M |
| | Service, Maintenance, Repair and Inspection for the Metropolitan Police Service's Overt Fleet. Procurement 5: Lot 1:… | London | £85M |
| | Bus Shelters and Information Panels (Advertising Concession) | Plymouth | £70M |
| | Hosting Capability Supplier | London | £70M |
| | Health System Strengthening in Sierra Leone | East Kilbride | £65M |
| | Media Planning, Buying and Attribution | London | £65M |
| | Refresh 2 - Care at Home Services Lots 2, 3 and 4 | Warwick | £64M |
| | Children's Residential Care, Fostering and Therapeutic Education Service | Taunton | £60M |
| | Recruitment MSP | Worthing | £60M |
| | Repair of Various Electrical Assemblies & Associated Items | Telford | £60M |
| | Mental Health Services Within Her Majesty's Prisons (HMP) | County Durham | £60M |
| | Winter Surge Capacity (21/22) | London | £59M |
| | Environmental Decontamination | Sheffield | £55M |
| | Managed Services for Temporary Agency Resources | Coventry | £52M |
| | NHS Education Frimley Health NHSFT | Leeds | £50M |
| | Car Parking Concession | London | £50M |
| | Costs Lawyer Services 2 | Liverpool | £50M |
| | Energy Efficiency Delivery Framework | London | £50M |
| | Leisure Centre Operation | Kent | £50M |
| | Low Energy Lighting & Radiant Heating Systems DPS | Wakefield | £50M |
| | Management of Affiliates and Aggregators | London | £50M |
| | Operating Partner for the National Outdoor Centre at Plas Menai, Gwynedd | Cardiff | £50M |
| | NHS Education Frimley Health NHSFT | Leeds | £50M |
| | SDF Lot 12.1 Central_ Jacobs U.K. Limited A | Birmingham | £43M |
| | SDF Lot 12.2 Central_ Jacobs U.K. Limited A | Birmingham | £43M |
| | Homes England Legal Services Framework 2022 | Coventry | £40M |
| | Traffic Management & Road Closures | London | £40M |
| | CF Combined Safety Syringes and Needles for COVID-19 Vaccination Programme - Morbidly Obese Requirement | London | £39M |
| | ESCC Housing -Related Floating Support | Lewes | £38M |
| | Nursing Home Beds Within Brighton and Hove | Hove | £38M |
| | SDF Lot 12.1 North East_ Jacobs U.K. Limited A | Birmingham | £38M |
| | Slow Sand Filter Beds and Rapid Gravity Filter Refurbishment Services and Media Supply | Reading | £36M |
| | DfI Roads and Rivers T-1112 Term Surface Dressing | Belfast | £35M |
| | SDF Lot 12.1 South East_ Jacobs U.K. Limited A | Birmingham | £32M |
| | Bi Borough Homecare Transformation | London | £32M |
| | Cladribine (Mavenclad®) | Edinburgh | £31M |
| | Non-Domestic Community Waste and Recycling Collection and Disposal Services | Leicester | £30M |
| | University Supply Chain Framework | Seascale | £30M |
| | A2Dominion Planned and Cyclical Works | London | £27M |
| | Open Access Sexual Health Services Are Statutory in Nature and Local Authorities Are Required to Provide… | Reigate | £27M |
| | Dynamic Maintenance - Condition Based Monitoring | Bradford | £26M |
| | Hire of Mobile Plant (With Operators) and Development Works at Lochhead Landfill Site | Glenrothes | £26M |
| | 344_22 Signs | Leicester | £25M |
| | Ground Based Surveillance Radar (GBSR) CFO | Bristol | £25M |
| | DfE Invest NI - Economic Services Framework Agreement | Belfast | £24M |
| | Household Waste Recycling Centres | Middlewich | £24M |
| | Juxtaposed Controls Services - Body Detection Dogs | Salford | £23M |
| | Communal Mechanical and Electrical Plant (Servicing, Planned Preventative Maintenance and Repair) | London | £22M |
| | Logistics Movement Support Services for British Forces Cyprus & SBA | Hq Bfc | £22M |
| | Design and Construction of 2 X Independent Living Projects - St Mellons & Maelfa | Cardiff | £22M |
| | Mental Health Services Within Her Majesty's Prisons (HMP) | Preston | £22M |
| | Automated Blood Sciences Managed Service | St Asaph | £22M |
| | Residential Care, and Care and Support to People With Learning Disabilities in the Hastings and Rother… | Lewes | £22M |
| | DfE TNI - Advertising and Marketing Services | Belfast | £21M |
| | Occupational Health Services Lot 1 - HMPPS | London | £21M |
| | Decontamination & Laundry Services | Seascale | £21M |
| | Demolition of and Development at 29-35 Russell Hill, Purley, Croydon CR 2LF | Leicester | £21M |
| | Hard Facilities Management | Coventry | £21M |
| | Demolition of and Development at 29-35 Russell Hill, Purley, Croydon CR 2LF | Leicester | £20M |
| | Fire Doors - Supply & Install and Also Supply Only | Southampton | £20M |
| | NHS.UK App | Leeds | £20M |
| | Intravenous & Topical Fluids | Edinburgh | £19M |
| | Stratford Waterfront Culture and Education Development - Public Realm - Hard and Soft Landscaping Works | Stratford | £19M |
| | NHS Education HEI With UNIVERSITY OF LEEDS | Leeds | £18M |
| | NHS Education HEI With UNIVERSITY OF LEEDS | Leeds | £18M |
| | Domiciliary Care Services in the Western Health and Social Care Trust Area | Derry | £18M |
| | Dental Sundries | Edinburgh | £18M |
| | Domiciliary Care Services in the Western Health and Social Care Trust Area | Derry | £17M |
| | General Building: Responsive Maintenance Framework | Northallerton | £17M |