| | Contractor Framework for Development Programme | London | £2B |
| | National Framework for Civils and Infrastructure | Gateshead | £860M |
| | Taxi and Minibus Services | Gateshead | £800M |
| | Locality Home Care & Support Service Framework - Including Locality Plus | Suffolk | £360M |
| | Bus Communications and Information System and Related Services | London | £318M |
| | Heavy Armour Post Design Services VTN | Bristol | £300M |
| | Multi Modality Imaging Equipment and Maintenance Framework | Edinburgh | £300M |
| | Microsoft Licence Renewal | Liverpool | £292M |
| | Operational, Management, Maintenance and Related Works and Services at Campsfield House IRC. The Content of This… | London | £227M |
| | Products for the Teratment of Haemophilia A | Runcorn | £215M |
| | FTL-Ss-VTN | Bristol | £191M |
| | Hyde Park Winter Wonderland 2018/19 -2023/24 | London | £173M |
| | Dynamic Purchasing System Domiciliary Care for Adults and Sessional Support for Children Young People and Families… | Cardiff | £156M |
| | Children's Residential Care Framework (Re-Opening) | Winchester | £147M |
| | Integrated Veterans Mental Health Service | Leeds | £133M |
| | Modification of the Radio Network Infrastructure Replacement Reference Number: RM6109 for Additional Services to Include Radio… | Southampton | £102M |
| | Ageing Well Care Homes Framework (Additional Round) | Nottinghamshire | £100M |
| | CHIC Adapted Bathroom Materials Supply Framework | Birmingham | £100M |
| | Existing Antimicrobial to the NHS in England | Leeds | £100M |
| | Existing Antimicrobial to the NHS in England via a Subscription-Based Payment Model | Leeds | £100M |
| | Hospital Electronic Prescribing and Medicines Administration Services | Cardiff | £100M |
| | New Antimicrobial to the NHS in England | Leeds | £100M |
| | New Antimicrobial to the NHS in England via a Subscription-Based Payment Model | Leeds | £100M |
| | Open Framework for Residential Care and Nursing Care of Older People Within the Borough of Barnsley… | South Yorkshire | £100M |
| | Improving Access to Psychological Therapy (IAPT) Services Across Nottingham, Nottinghamshire and Bassetlaw | Nottingham | £97M |
| | Parking Services. Lot 1 - Business Processing, Lot 2 People & Resources, Lot 3 Abandoned Vehicles… | London | £92M |
| | Dry, Chilled and Frozen Goods | Hampshire | £90M |
| | Dry, Chilled and Frozen Foods | Winchester | £88M |
| | Inpatient and Outpatient Healthcare Services and Hospital Capacity, as Part of the Response to the Covid-19… | Leeds | £87M |
| | Consultants Framework for Development Programme | London | £82M |
| | Development at Elwick Place, Ashford, Kent | Ashford | £80M |
| | Responsive Repairs and Minor Works | Leicester | £72M |
| | NHS National Generic Pharmaceuticals - Lenalidomide | Runcorn | £70M |
| | Merchant Acquirer Services | Swansea | £69M |
| | Highways and Infrastructure Professional Services | Reigate | £51M |
| | SCC AM Highways and Infrastructure Professional Services | Reigate | £51M |
| | Market Engagement PIN for the Mobile Infrastructure Monitoring Delivery Strategy | London | £50M |
| | OLE Renewal OLE Mid Life Refurbishment Fenchurch Street to Pitsea | London | £50M |
| | Crime Survey for England and Wales (CSEW) | Newport | £47M |
| | Hard Facility Management Services | Plymouth | £45M |
| | Hard Facilities Management Services | Plymouth | £45M |
| | BeST HA Repairs and Voids | Manchester | £45M |
| | BSH/ HRA Responsive Repairs Framework | Bristol | £45M |
| | HS1 Electricity Supply (ESC) | London | £45M |
| | Media Buying | Liverpool | £45M |
| | Security Guarding Service for the High Commission and Residence in Port of Spain | London | £44M |
| | Integrated Sexual and Reproductive Health Services | Bradford | £43M |
| | Educational Services Procured Services Arrangement (PSA) | Hamilton | £42M |
| | BeST HA Repairs and Voids | Manchester | £40M |
| | Building Cleaning Services | Hertford | £40M |
| | J834 PSTN & RTU Obsolescence Replacement Programme | Reading | £40M |
| | Digital Integration and Service Operations | London | £40M |
| | International Pathway Programmes | Loughborough | £35M |
| | Transparency Notice - Amphora 2 | Bristol | £35M |
| | NHS Education With University Hospitals Plymouth NHS Trust | Leeds | £35M |
| | NHS Education With University Hospitals Plymouth NHS Trust | Leeds | £35M |
| | NHS Education With Royal Devon and Exeter NHS Foundation Trust | Leeds | £34M |
| | NHS Education With Royal Devon and Exeter NHS Foundation Trust | Leeds | £34M |
| | Digital Integration and Service Operations | London | £34M |
| | NHS Education With Royal Cornwall Hospitals NHS Trust | Leeds | £34M |
| | Framework Alliance Agreement RM6088: Call-Off Project CWAS-071-2020 - Leuchars Station Phase 5 | Glasgow | £33M |
| | Islington Council Term Service Highway Works | London | £32M |
| | NHS Education With Somerset NHS Foundation Trust | Leeds | £31M |
| | NHS Education With Somerset NHS Foundation Trust | Leeds | £31M |
| | Repairs Maintenance and Improvement Works | Plymouth | £30M |
| | Strategic Partnership for Technical Services Framework | Scorrier | £30M |
| | Timber Materials | London | £30M |
| | External Envelope Enhancement Programme | Kilmarnock | £28M |
| | Small Children's Residential Homes for Children and Young People With Complex Needs | Derby | £28M |
| | Design & Build of Research Offices | Abingdon | £27M |
| | Grovehurst Road Amd Key Street | Maidstone | £27M |
| | Grovehurst Road and Key Street | Maidstone | £27M |
| | Cleaning Services | Grimsby | £25M |
| | Sustainable Fleet Solutions | Salford | £25M |
| | Contrast Media Agents | Edinburgh | £24M |
| | Hire of Trenching & Shoring Equipment | Glasgow | £24M |
| | Relating to Stafford Further Education College, Skills and Lnnovation Centre Incorporating the Conditions of the JCT… | Manchester | £24M |
| | NHS Education With Peninsula Dental Social Enterprise | Leeds | £23M |
| | NHS Education With Peninsula Dental Social Enterprise | Leeds | £23M |
| | Out of Work Service | Cardiff | £22M |
| | Demolition of and Development at 29-35 Russell Hill, Purley, Croydon CR 2LF | Leicester | £20M |
| | Specialist Homecare Services on the Isle of Wight | Newport | £20M |
| | Estates Management Professional Services | Leicester | £20M |
| | Further Competition for Care and Support Services (Harelaw Development) | Durham | £20M |
| | Hypodermic Needles and Syringes | Belfast | £18M |
| | Design, Supply, Installation and Maintenance of Intelligent Transport Systems | Matlock | £17M |
| | DHSC: GO - Single eCommercial System for DHSC, Health Family and the NHS | London | £17M |
| | CSI/ED/Therapists, Mentors and Tutors Approved Provider List | Bristol | £16M |
| | Services-DPS-Engineering, Programme Management & Commercial Resources | Warrington | £16M |
| | Overnight Short Breaks Services for Children and Young People With Special Educational Needs and Disabilities (SEND)… | Hertfordshire | £16M |
| | DOJ PSNI Managed Service Requirement ANPR | Belfast | £15M |
| | Month Extension | Blackpool | £15M |
| | Digital Services for Co-Managed Care | Glasgow | £15M |
| | Hard Facilities Maintenance at the National Gallery and National Portrait Gallery | London | £15M |
| | Material Recovery Facilities | Middlewich | £15M |
| | Vacant Property: Protection, Clearance, Cleaning and Maintenance Extension Notice | Uxbridge | £15M |
| | Design and Build of Solar PV Farms and Nethermains, Kilwinning and Shewalton, Irvine | Irvine | £15M |
| | NHS Education With Yeovil District Hospital NHS Foundation Trust | Leeds | £15M |
| | NHS Education With Yeovil District Hospital NHS Foundation Trust | Leeds | £15M |
| | Beds and Mattresses Fully Managed Services | Nottingham | £14M |