| | Supply of Energy 2 | Liverpool | £51B |
| | Payment Card Services | Gateshead | £6B |
| | Supporting Vulnerable Adults Dynamic Purchasing Vehicle | London | £957M |
| | NHS Framework for Midlands and East Branded Medicines - Tranche B and Annual Tranche | Leeds | £876M |
| | Framework Construction Works | Gateshead | £800M |
| | NHS Framework for North of England Branded Medicines - Tranche A and Annual Tranche | Leeds | £654M |
| | Generation 3 Construction Framework | Glasgow | £500M |
| | NHS Framework for Midlands and East Branded Medicines - Tranche B and Annual Tranche | Runcorn | £438M |
| | Temporary and Semi-Permanent Buildings | West Malling | £400M |
| | Campsfield House and Haslar IRCs Procurement | London | £399M |
| | Operational, Management, Maintenance and Related Works and Services at Campsfield House IRC and Haslar IRC. Content… | London | £399M |
| | NHS Framework for North of England Branded Medicines - Tranche A and Annual Tranche | Runcorn | £327M |
| | Home Support for Norfolk 4th Re-Opening | Norwich | £300M |
| | NHMF Frameworx Responsive Maintenance and Void Property Works | Mitcham | £300M |
| | NHS National Generic Pharmaceuticals Wave 14a | Runcorn | £263M |
| | Peninsula Residential Children's Homes Flexible Purchasing System (FPS) | Exeter | £225M |
| | Minster Quarter Reading- Development | Reading | £220M |
| | Software Value Added Reseller Services | Glasgow | £200M |
| | WHG Planned Programme Works 2022-29/32 | Walsall | £197M |
| | 704395456 FTL-Ss | Bristol | £191M |
| | Procurement and in-Service Support of Fused Target Locator (FTL) and Associated Ancillaries | Bristol | £191M |
| | Pulse Oximetry, Capnography and Related Patient Monitoring Technologies | London | £145M |
| | Health and Social Care in Her Majesty's Prisons | Preston | £145M |
| | Staffordshire University Student Village DBFO Project | Stoke on Trent | £134M |
| | Health and Social Care | Liverpool | £120M |
| | Staffordshire University Student Village DBFO Project | Stoke on Trent | £120M |
| | UK Government Centres of Expertise: Green Cities and Infrastructure (GCI) | London | £119M |
| | Intravenous Cannula and Associated Products | London | £113M |
| | Eculizumab | Leeds | £112M |
| | Buying Better Foods | Liverpool | £100M |
| | Cirrus Consortium Agency Labour and Recruitment Services Framework | Cheshire | £100M |
| | Hybrid Outsourced Outpatient Pharmacy Dispensing Services | Fulbourn | £100M |
| | Next Generation Countermeasure Notice | Bristol | £100M |
| | WHG Planned Programme Works 2022-29/32 | Walsall | £83M |
| | NHS Bath and North East Somerset, Swindon and Wiltshire Integrated Care Board - Integrated Urgent Care… | Chippenham | £81M |
| | Agency Workers to the Northern Ireland Housing Executive | Belfast | £56M |
| | Project Numidian Tender Documents for Transparency | Andover | £54M |
| | Communication Solutions and Associated Telephony Services | West Malling | £50M |
| | Microbiology Managed Equipment Service | Birmingham | £50M |
| | Tyne-Tees Independent Foster Care Services (C-012130) OPENING 1 | Newcastle upon Tyne | £50M |
| | Scarborough, Selby & Misc Local Bus Services and Hambleton, Scarborough, Selby Mainstream Home to School Transport,… | Northallerton | £48M |
| | Scarborough, Selby & Misc Local Bus Services and Hambleton, Scarborough, Selby Mainstream, & Misc | Northallerton | £48M |
| | ICB Has Set Higher and Lower Budgetary Thresholds for Each Lot Which Is Explained Within the… | Glenfield | £46M |
| | Patient Transport Services (PTS) for the Leicestershire Integrated Board (ICB) | Glenfield | £46M |
| | Responsive Maintenance, Void Property Works, Planned Maintenance and Compliance Works | Belfast | £42M |
| | Services Covering Gedling, Rushcliffe, Broxtowe, Mansfield and Ashfield | Nottinghamshire | £42M |
| | Bloom Procurement Services Limited | London | £40M |
| | Eculizumab | Runcorn | £37M |
| | Adult Substance Mis-Use Recovery System | Doncaster | £35M |
| | Sefton Council Healthy Child Programme (Up to 25 With SEND) | Bootle | £32M |
| | Audiological Equipment Services and Related Consumables | London | £30M |
| | CVL Transformation - Rhymney Valley Line Electrification | Pontypridd | £30M |
| | Leadership Academy Faculty Framework | London | £30M |
| | Managed Print Solutions Framework Agreement | Glasgow | £30M |
| | Supply & Distribution of Milk | Paisley | £26M |
| | Salary Sacrifice Electric Vehicle Lease and Maintenance | Belfast | £24M |
| | DSA Collection & Process | Leeds | £24M |
| | Highlight Leisure Centre | Hartlepool | £22M |
| | Impact Evaluation of the Interventions Funded by the Violence Reduction Unit | South Yorkshire | £22M |
| | Full Service Now License Renewal | Telford | £21M |
| | Eastern Region - Possession Management | London | £21M |
| | Holiday Activities and Food Schemes | Winchester | £20M |
| | Medway Council's Temporary Agency Staff - Dynamic Purchasing System | Chatham | £20M |
| | National Nature Reserves (Natural England) X 9 Major Build Programme | London | £20M |
| | NHS Low Calorie Diet Programme | Leeds | £20M |
| | Speed Awareness Courses | London | £18M |
| | Washroom Solutions | Paisley | £18M |
| | Radiation Monitoring Network | London | £17M |
| | Sexual Assault Referral Centre (SARC) Service | Leeds | £17M |
| | PIN - SEND Buses | London | £16M |
| | Plant Hire Owner Operated | Matlock | £16M |
| | Term Service Major and Minor Disabled Adaptations | Beverley | £16M |
| | Construction of a New UTC at Ipswich Hospital | Colchester | £15M |
| | DWP Notification Service | Manchester | £15M |
| | Independent Investigations | Leeds | £15M |
| | Mental Health Supported Housing & Outreach Services | London | £15M |
| | Veterans in the Criminal Justice System (VCJS) - A Single Pathway for Veterans in England | Nottingham | £14M |
| | Tech Enabled Care (Telecare) | Liverpool | £13M |
| | Forestry England Forest Fencing DPS | Bristol | £13M |
| | Intermediate Care Services | Glasgow | £12M |
| | Staffordshire and Stoke-on-Trent Wheelchair Service | Stoke on Trent | £12M |
| | Dental Sundries | Edinburgh | £12M |
| | Street Manager Continuous Improvement & Support | London | £12M |
| | Women's Core Costs Funding 2022 | Manchester | £12M |
| | Services for Women, Children and Young People Who Have Experienced Domestic Abuse | Edinburgh | £12M |
| | Child Health Information Services (CHIS) South West | Durham | £12M |
| | Child Health Information Services (CHIS) South West | Chippenham | £12M |
| | Digital Delivery Partner | London | £12M |
| | Highway Construction and Plumbing Materials Framework (CPU | Nottingham | £11M |
| | St Clements House, Corporation Street, Rochester, Kent, ME1 1NH | Chatham | £11M |
| | Semi-Indep Living | Reading | £11M |
| | Hounslow Integrated Health and Wellbeing Service | Hounslow | £10M |
| | Leadership & Management Direct Delivery | Peterborough | £10M |
| | Academic & SME Support Services | Milton Keynes | £10M |
| | Digital Advertising Framework | Braintree | £10M |
| | EKFB JV - Land Maintenance | Birmingham | £10M |
| | E&P Reactive, Minor Works and Renewals and SPS Renewals | London | £10M |
| | Highways Construction Materials Framework | Dorchester | £10M |
| | Refugee Resettlement Services Framework 2022 | Liverpool | £10M |
| | Specialist Support Services 2022/23 | London | £10M |