| | G-Cloud 13 | Liverpool | £4B |
| | SCAPE Civil Engineering Framework - England, Wales and Northern Ireland | Nottingham | £3B |
| | SCAPE Civil Engineering Framework - EWNI | Nottingham | £3B |
| | NHS National Proprietary Pharmaceuticals | Runcorn | £2B |
| | Medium-Term Residual Waste Treatment | Chelmsford | £867M |
| | SCAPE Civil Engineering Framework - Scotland | Edinburgh | £750M |
| | Digital Services Framework Agreement | London | £562M |
| | Generation Five (Gen5) Civil Engineering, Highways and Transportation Collaborative Framework 2024 | Winchester | £500M |
| | New Build Framework | Newcastle upon Tyne | £500M |
| | Pre Market Engagement - SY ICS Pathology Managed Equipment Service | Sheffield | £500M |
| | Software License Resellers Agreement (SLRA) | Reading | £500M |
| | Suffolk Construction and Building Services Framework | Ipswich | £500M |
| | Thirteen Housing Group Strategic Partner Construction Framework | Co Durham | £500M |
| | NHS National Proprietary Pharmaceuticals - Category | Runcorn | £428M |
| | Integrated Single Financial Environment | London | £350M |
| | Group Energy Commodity | Manchester | £320M |
| | Construction Partnering Framework | Preston | £300M |
| | Grocery, Frozen and Chilled Products | Manchester | £300M |
| | LPS CAS - Construction Partnering Framework | Preston | £300M |
| | Patient Discharge and Mental Health Step Down Care Services | Hemel Hempstead | £300M |
| | Contracts C861 / C862 Modification | Birmingham | £260M |
| | T-CE Highways Services Partner | Shefford | £250M |
| | NHS Midlands and East Branded Medicines - Tranche B - March | Runcorn | £246M |
| | Northern Ambulance Alliance (NAA) Common CAD (Computer Aided Dispatch) System | Wakefield | £240M |
| | Northern Ambulance Alliance (NAA) Common Computer Aided Dispatch (CAD) | Wakefield | £240M |
| | MSE Office Supplies, Furniture & Print Services DPS | Southend | £200M |
| | Print Marketplace | Liverpool | £200M |
| | Travel Management Solution II | Wakefield | £200M |
| | NHS Midlands and East Branded Medicines - Annual Tranche March | Runcorn | £192M |
| | NHS North of England Branded Medicines - Annual Tranche March | Runcorn | £190M |
| | NHS South of England Branded Medicines - Tranche B - September | Runcorn | £185M |
| | LAN Services | London | £180M |
| | Construction & Refurbishment of Distribution Overhead Lines | Belfast | £157M |
| | NHS South of England Branded Medicines - Annual Tranche - September | Runcorn | £154M |
| | Healthcare - Design, Furniture & Appliances | Hemel Hempstead | £150M |
| | Human Resources, Payroll and Employee Screening Services | Salford | £150M |
| | NHS London Branded Medicines - Annual Tranche -September | Runcorn | £150M |
| | NHS London Branded Medicines - Tranche B - September | Runcorn | £150M |
| | NHS North of England Branded Medicines - Tranche B - March | Runcorn | £144M |
| | Painting, Decorating and Associated Repairs Framework | Prescot | £125M |
| | WHC - Housing Maintenance Services | Welwyn Garden City | £120M |
| | Independent Providers of Foster Care Services | Lewes | £112M |
| | National Driver Offender Retraining Schemes for North, South and West Yorkshire Police | Leeds | £110M |
| | NHS London Branded Medicines - Annual Tranche -September | Runcorn | £107M |
| | Procurement Solutions Tool | Leeds | £102M |
| | Electric Vehicle Charging Infrastructure and Associated Services | Oxford | £100M |
| | Major Permissions Delivery Partner | Didcot | £100M |
| | Major Permissions: Delivery Partner | Didcot | £100M |
| | Occupational Health Services | Leicester | £100M |
| | Preferred Supplier Listing for Umbrella Payment Services | West Malling | £100M |
| | Mole Valley District Council - Leisure Centre Management | Dorking | £95M |
| | NHS England (Midlands) - HMP Birmingham - Healthcare Services | Rugeley | £89M |
| | NHS England (Midlands) HMP Birmingham - Healthcare Services | Rugeley | £89M |
| | Temporary Agency Staffing | Aylesbury | £88M |
| | NHS Midlands and East Branded Medicines - Tranche A - March | Runcorn | £82M |
| | NHS North of England Branded Medicines - Tranche A- March | Runcorn | £82M |
| | Preferred Supplier Listing for Umbrella Payment Services | West Malling | £80M |
| | Patient Discharge and Mental Health Step Down Care Services | Hemel Hempstead | £75M |
| | NHS National Proprietary Pharmaceuticals - Eculizumab Biosimilar | Runcorn | £74M |
| | Forest Nets Concession Opportunity | Bristol | £73M |
| | Care at Home | Warrington | £70M |
| | NHS App | Leeds | £66M |
| | Personal Independence Payment (PIP) Assessment Service Extension - Lot 1 | Sheffield | £62M |
| | NHS National Proprietary Pharmaceuticals - Low Molecular Weight Heparins | Runcorn | £61M |
| | NHS National Proprietary Pharmaceuticals - Eculizumab Biosimilar | Runcorn | £60M |
| | Transport Services for Vulnerable Children and Adults (DPS) - ASCHIW/2022/316* | Stoke on Trent | £57M |
| | Personal Independence Payment (PIP) Assessment Service Extension - Lot 3 | Sheffield | £55M |
| | DSA - Data Products, MI and Data Feed Re-Engineering | London | £55M |
| | NHS South of England Branded Medicines - Tranche A - September | Runcorn | £54M |
| | Personal Independence Payment (PIP) Assessment Service Extension - Lot 2 | Sheffield | £54M |
| | Technology Enabled Care Services (TECS) | Maidstone | £53M |
| | Crematoria Solutions III | Wakefield | £50M |
| | Dynamic Purchasing System for Passenger Transport Services | Norwich | £50M |
| | Command and Control System | Bridgend | £48M |
| | NHS London Branded Medicines - Tranche A - September | Runcorn | £47M |
| | Substance Misuse Services | Lincoln | £46M |
| | DGM/1958 | Bristol | £45M |
| | Laboratory Managed Serivce | Birmingham | £41M |
| | Rotary Wing Command Support Air Transport Helicopter Service (RWCSAT) | Bristol | £40M |
| | Rotary Wing Command Support Air Transport Helicopter Service (RWCSAT Notice | Bristol | £40M |
| | Public Health Healthy Child Programme - 0-19 Public Health Nursing | Derby | £40M |
| | Security QA & Engineering Services | London | £36M |
| | Human Resources, Payroll and Employee Screening Services | Salford | £35M |
| | Planned Installation & Repairs Framework Agreement | Salford | £35M |
| | Supported Living for Adults and Older People | Glenrothes | £34M |
| | Temporary Agency Allied Health Professionals & Other Clinical Professions | Edinburgh | £33M |
| | Next Flood Warning System (NFWS) | London | £32M |
| | Parking and Traffic Enforcement and Associated Services | Kingston upon Thames | £30M |
| | Cloud Services | Glasgow | £30M |
| | NOISE BARRIERS - Earthworks, Construction and Installation - High Speed 2 (HS2) | Birmingham | £30M |
| | Unmetered Electricity 2023-2024 (ID | Belfast | £30M |
| | Technology Enabled Care Services (TECS) | Maidstone | £28M |
| | Natural Gas | Belfast | £28M |
| | Maintenance of Catering Equipment [4597785] | Ballymena | £27M |
| | Implementation Support Services (ISS) | Birmingham | £26M |
| | Community Based Day Opportunities Q1 1st July 2022 to 30th September | Stafford | £25M |
| | Car Sharing Solution | London | £24M |
| | Creation and Management of Independent Alternative Provision Schools | Wakefield | £24M |
| | Derby Integrated Drug and Alcohol Recovery System | Derby | £22M |
| | Grounds Maintenance, Street Cleansing and Building Cleansing Services | Benfleet | £22M |