HUTH/23/003 PromethION DNA / RNA Gene Sequencing Machine

Location

Kingston Upon Hull:

Description

This notice is being published to inform of an award of a contract to Oxford Nanopore Technologies for a PromethION DRA / RNA Gene Sequencer.

Total Quantity or Scope

The Trust has been awarded external UKRI funding to purchase an Oxford Nanopore Technologies (ONT) Promethion 24 sequencing device. This is to support several defined long-read sequencing projects, and wider research objectives. A condition of the funding is that this must be delivered by the end of March 2023.

Award Detail

CPV Codes

• 38434540 - Biomedical equipment
• 73111000 - Research laboratory services

Legal Justification

The Trust has been awarded external UKRI funding to purchase an Oxford Nanopore Technologies (ONT) Promethion 24 sequencing device. This is to support several defined long-read sequencing projects, and wider research objectives. A condition of the funding is that this must be delivered by the end of March 2023. Metagenomics is a rapidly emerging field, evaluating the composition and function of the microorganisms that inhabit an environment (eg. body sites/clinical samples). The interactions between these microorganisms and our bodies cells are important for both health and pathology. From the research undertaken by the Trust we understand that ONT is the sole provider of long-read nanopore sequencing, in particular: 1. ONT Promethion is able to deliver >30M long-read RNA and DNA sequences from any metagenomic sample from a single flow cell. The sequences are routinely >3Kb in length. The ONT technology is able to uniquely deliver sub-species level characterisation of community composition. 2. ONT Promethion includes real-time adaptive sequencing capabilities. This means that samples can be enriched for specific sequences during the data generation which is essential to overcome host contamination in clinical metagenomics samples.

Other Information

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