| | NHS Increasing Capacity Framework | Leeds | £10B |
| | Travel and Venue Solutions | Liverpool | £5B |
| | Training Service to the Royal Navy and Royal Marines | Hampshire | £2B |
| | Contractor Framework | Wembley | £1B |
| | Northamptonshire County Council - Highway Services (On Behalf of West and North Northamptonshire Councils) | Northampton | £1B |
| | Northamptonshire County Council - Highway Services (On Behalf of West Northamptonshire and North Northamptonshire Councils) | Northampton | £1B |
| | Private Sector Development Partner for the South East Territory | Edinburgh | £1B |
| | Medicinal Products and Pharma Funded Homecare Services | Belfast | £900M |
| | Scape National Consultancy Framework | Nottingham | £700M |
| | Design, Renovation, Operational, Management, Maintenance and Related Works at Heathrow Immigration Removal Centre And; Operational, Management,… | London | £514M |
| | Audit & Assurance Services (A&AS) Framework | Liverpool | £500M |
| | Audit Assurance Services (AAS) Framework | Liverpool | £500M |
| | National Desktop and Notebook Agreement | London | £500M |
| | YPO - Alternative Fuelled Vehicles DPS | Wakefield | £500M |
| | Campaign Solutions 2 | Liverpool | £490M |
| | Temporary Accommodation Flexible Purchasing System | Edinburgh | £430M |
| | Scape National Consultancy Framework | Nottingham | £350M |
| | Employee Benefits for Health, Wealth and Wellbeing Framework | Sheffield | £300M |
| | Grand Union Housing Electricity and Gas Procurement Framework | Milton Keynes | £300M |
| | Temporary Agency Workers for Northern Ireland Civil Service, Agencies and Non Departmental Public Bodies | Belfast | £300M |
| | Testing Contact Centre | London | £259M |
| | Trader Support Service | London | £241M |
| | Covid-19 Testing Site Facilities Management | London | £221M |
| | Living Well at Home - Dynamic Framework Agreement | Oxford | £214M |
| | Communications Marketplace | Liverpool | £210M |
| | Maintenance and Management TfL Road Tunnels and Pumping Stations | London | £200M |
| | WBC Town Hall Quarter - Development Partner Procurement | Watford | £200M |
| | Living Well at Home - Dynamic Framework Agreement | Oxford | £190M |
| | Dynamic Approved Provider List for Residential and Nursing Care Services to Older People Older People Requiring… | Cardiff | £180M |
| | Adult Education Budget Procurement Contracts for Services 2021/22 | Coventry | £157M |
| | Regulated Homecare Services: For Providers in Somerset | Taunton | £155M |
| | National for Waste Management and Minimisation | Chester | £136M |
| | EWR Co. Scheme Development Phase Technical Partner | London | £110M |
| | Grand Union Housing Electricity and Gas Procurement Framework | Milton Keynes | £100M |
| | Mechanical Handling and Lifting - Material Supply and Repair | Bristol | £98M |
| | Solihull Town Centre Low Carbon Energy Network | Solihull | £80M |
| | SOL - Solihull Town Centre Low Carbon Energy Network | Solihull | £80M |
| | Smart Motorways Alliance - Technology Procurement | London | £75M |
| | SMA Technology Procurement Category | London | £75M |
| | Travel Management Services Framework for Northern Ireland Civil Service, Agencies, Non-Departmental Public Bodies and Other Participating… | Belfast | £75M |
| | Residential and Nursing Care Services | Walsall | £68M |
| | Housing Repairs and Maintenance | Ilford | £63M |
| | Serology - Rapid Antibody Test Kits | London | £62M |
| | Learning Disability Open for Providers in Somerset | Taunton | £60M |
| | Supportive Medicines - Additional Products (ITU, Antibiotics EOI Medicines)Open Supportive Medicines - Additional Products (ITU, Antibiotics… | London | £60M |
| | Surge (With Variations 1-4) | London | £59M |
| | Critical Communications Infrastructure Framework | Wakefield | £50M |
| | Regent’s Park Art Fair 2022 | London | £50M |
| | Vehicle Parts | Paisley | £48M |
| | Hawk T Mk2 In-Service-Support Extension | Bristol | £42M |
| | Power Purchase Agreement for Off-Site Renewable Electricity | London | £40M |
| | WHHT - Electronic Patient Record Services | Welwyn Garden City | £40M |
| | Construction of New Housing Developments Framework | Kirkintilloch | £38M |
| | Greenwich Schools Food and Catering Services Framework Agreement | London | £38M |
| | Flexible Framework for Early Learning and Childcare Services in North Lanarkshire 2020/2023 - Entry Point 2… | Motherwell | £36M |
| | St Marks CofE All-Through School | Southampton | £35M |
| | Nutritional Products, Administration, Consumables and Associated Services | Belfast | £31M |
| | Kerbside Collection, Street Cleaning, Management of HWRC's and HWRC Transport Extension (2022-24) | Oakham | £30M |
| | Power Purchase Agreement for Off-Site Renewable Electricity | London | £30M |
| | Legal Services | London | £30M |
| | Oncology Generics Medicines | Edinburgh | £29M |
| | Audiology Products | Cardiff | £27M |
| | Training in Lean Project Management and Programme Management Skills — DPS for Skills Providers and Training… | Chester | £27M |
| | Services for the Transfer, Management and Treatment of Green, Food, Bulky and Wood Waste | Aylesbury | £27M |
| | Early Learning, Childcare and Brokerage Services | Dumfries | £25M |
| | Tocilizumab Subcutaneous Injection (RoActemra®) | Edinburgh | £25M |
| | Audit Services | Salford | £25M |
| | Specialist Bridges Inspection and Maintenance | Leeds | £24M |
| | CLA Minor Civils Package 1 20-21 | Bristol | £23M |
| | Re-Development of Thamesview House | Leicester | £22M |
| | PHE - PHE Porton FM Hard Services | Porton | £22M |
| | Spennymoor the Oaks -Render Works | Durham | £22M |
| | Blashford Estate - Main Works Contractor | London | £22M |
| | Blashford Tower, Major Works Project | London | £22M |
| | Job Entry: Targeted Support Scotland Mini- Competition | London | £22M |
| | General Building Works | Bath | £20M |
| | In Service Support for Hawk T Mk1/1a Aircraft | Bristol | £20M |
| | Ready Meals | Leicester | £20M |
| | Residential Care Accommodation for People With a Learning Disability and/or Autism Within the Borough of Stockton-On-Tees… | Stockton on Tees | £20M |
| | Tier 3 Community Accommodation Services: Prior Information Notice | London | £20M |
| | Vehicle Conversions | Edinburgh | £17M |
| | NHS National Generic Pharmaceuticals Interim 2 | Runcorn | £17M |
| | Personal Protective Equipment for Healthcare Workers for the Care of Patients With Suspected or Confirmed Novel… | London | £16M |
| | Lateral Flow Test Kits for Testing of COVID-19 | London | £16M |
| | In-Service-Support and Availability of Adour Engines for Hawk T Mk1/1A and Hawk T Mk2 Aircraft | Bristol | £15M |
| | Minor Engineering Works Framework 2022 | Exeter | £15M |
| | Orthopaedic Spinal and Scoliosis Implants, Consumables and Equipment | Edinburgh | £15M |
| | Orthopaedic Spinal Scoliosis Implants, Consumables Equipment | Edinburgh | £15M |
| | Supported Housing Accommodation and Housing Related Support Services | Lincoln | £15M |
| | Washroom Services | Manchester | £15M |
| | Project and Cost Management Services | Salisbury | £15M |
| | UK Real Investment Management for Hampshire County Council Pension Fund | Winchester | £14M |
| | River Learning Trust - Catering Services | Kidlington | £14M |
| | Serology - Rapid Antibody Test Kits | London | £13M |
| | Camden Building Term Service 5 - Fire Safety Works | London | £13M |
| | Statutory Transport Journeys on Behalf of North Ayrshire Council | Irvine | £13M |
| | Rigid/Semi-Rigid Telescopes, Ancillary Equipment and Accessories | Antrim | £13M |
| | West Midlands Bike Share Scheme | Birmingham | £12M |
| | Personal Dental Services (PDS) in London Prisons and Heathrow Immigration Removal Centre | London | £12M |
| | Personal Dental Services (PDS) in London Prisons and Heathrow Immigration Removal Centre | Leeds | £12M |