| | Environmental Decontamination | London | £78B |
| | Homecare Medicines Services | Fulbourn | £13B |
| | NHS Workforce Alliance Healthcare Solutions | Liverpool | £10B |
| | Future Defence Support Services (FDSS) | Bristol | £8B |
| | Total Facilities Management | London | £7B |
| | Collaborative Delivery Framework 2 | London | £5B |
| | UKHSA Diagnostics and Research Open Framework | London | £5B |
| | Southern Construction Framework (SCF-6) | Exeter | £4B |
| | Plymouth Heat Networks Development Partner | Plymouth | £4B |
| | Non Clinical Staffing 2 | Liverpool | £2B |
| | Pharmaceutical Wholesale Services 25 | Leeds | £2B |
| | Sustainable Estates Solutions Framework Agreement | Dorking | £2B |
| | Pipeline Notice - Defence Water Services Programme -UK1 | Lichfield | £2B |
| | YORBuild Major Works 2 | Leeds | £2B |
| | Media and Creative Framework | Liverpool | £1B |
| | Older Persons Residential and Nursing | Maidstone | £1B |
| | Patient Healthcare Communications and Related IT Services Framework | Dorking | £1B |
| | Network & Telecommunications Procurement Project (NTPP) | London | £1B |
| | Beach Management Framework | London | £1B |
| | Recruitment Services for the Army | Upavon | £1B |
| | Non Emergency Patient Transport Open Framework | London | £1B |
| | Extra Care Plus - Future Provision | Northallerton | £850M |
| | Rehabilitative Services for Men in Prison or in the Community | London | £849M |
| | Rehabilitative Services for Men in Prison or the Community | London | £849M |
| | STFC Construction Partner | Swindon | £800M |
| | Independent and Non-Maintained Special Schools (INMSS) | Chichester | £755M |
| | Light Mobility Vehicle | Bristol | £750M |
| | BHRUT / NEL ICB 2023/25 Acute Variation 3 | London | £696M |
| | Programme Support Works Framework | Milton Keynes | £675M |
| | Insulation and Associated Works Framework | Alfreton | £650M |
| | Highways and Infrastructure Works Framework | Birmingham | £640M |
| | Single Use Theatre Protective Wear and Related Consumables | London | £625M |
| | National Proprietary Framework for HIV and Preventative Treatments | London | £625M |
| | Essex Child and Family Wellbeing Service (ECFWS) | Chelmsford | £600M |
| | Prison Operator Services HMP Oakwood | London | £600M |
| | Residential Care Framework (Adults) | Southampton | £600M |
| | Homecare Framework | Huntingdon | £592M |
| | Infrastructure Services | London | £575M |
| | Actuarial, Benefits and Governance Consultancy Services | Norwich | £500M |
| | Construction & Building Services Framework | Ipswich | £500M |
| | Food, Beverage & Retail Income Arrangements and Associated Services | Leatherhead | £500M |
| | HMRC Contact Centre as a Service (CCaaS) Procurement | London | £500M |
| | Westminster Housing Repairs and Works Contracts (Including Repairs, Maintenance, Voids, Domestic Heating, Mechanical, Electrical, Lifts and… | London | £500M |
| | Planned Works 2026_cas-01066-L2V8S5 | Devizes | £495M |
| | Accommodation and Support | Ipswich | £490M |
| | LirIC EPCI HVDC Interconnector Converter Stations | London | £453M |
| | Neurology, Spine Surgery Goods and Services | Birmingham | £435M |
| | Technology Partner for Metrolink Supervisory and Controls System Renewal | Manchester | £417M |
| | Building Materials | Preston | £400M |
| | Digital Dictation, Speech/Voice Recognition, Outsourced Transcription and Associ | Dorking | £400M |
| | Digital Dictation, Speech/Voice Recognition, Outsourced Transcription and Associated Services | Dorking | £400M |
| | Digital Primary Care | London | £400M |
| | Homes England - Independent Distribution Network Operator (IDNO) Led Integrated Utility Framework | Newcastle upon Tyne | £400M |
| | Planned and Responsive Framework | Preston | £400M |
| | Primary Care Support Services | Leeds | £385M |
| | Primary Care Support Services- Records Management, Logistics & Supplies | Leeds | £385M |
| | Railway (GSM-R) Long Term Support (Voice Frequentis) Framework | London | £378M |
| | Children's Homes and Special Education | Norwich | £350M |
| | Primary Care Support Services | Leeds | £350M |
| | Primary Care Support Services- Administration | Leeds | £350M |
| | T3 - Test Centre Network (TCN) - All Regions | Bristol | £350M |
| | Future Theory Test Service (FTTS) Test Centre Network (TCN) - Modification | Nottingham | £347M |
| | Managed Equipment Service & Consumables - Cardiology and Imaging | Leicester | £342M |
| | Humanitarian Emergency Response Operations and Stabilisation (HEROS) | London | £330M |
| | Application Services Re-Procurement | London | £325M |
| | Materiel Distribution Land (MDL) Heavy Equipment Transporter (HET) UK1 | Bristol | £315M |
| | NHS London & South of England Branded Medicines - Tranche B | London | £315M |
| | Passive Fire Protection Services Framework | Alfreton | £310M |
| | LirIC EPCI HVDC/AC Cables Supply and Install | London | £304M |
| | Building Works Framework 2025/26 | London | £300M |
| | Learning Disability, Mental Health and Autism Specialist Supported Accommodation Framework | Huntingdon | £300M |
| | Supplier Performance Framework 3 | London | £300M |
| | Window and Doors Framework | Alfreton | £300M |
| | Home Delivery Service - Home Parenteral Nutrition | London | £296M |
| | Single Service Centre (SSC) - New With Effect From Nov | London | £295M |
| | New Citizen Experience Contact Centre (S) for BAU & Surge Requirements | London | £295M |
| | EHR Project | Taunton | £289M |
| | Tender Notice - Syringes, Needles and Associated Products | London | £284M |
| | Framework for Major Projects (D&B) | Birmingham | £264M |
| | Interim/Agency Workers 2025 (In Collaboration With TfL - TfL Leading) | London | £262M |
| | NHS Generic Pharmaceuticals - Wave 15c | London | £260M |
| | NHS Generic Pharmaceuticals - Wave 16a | London | £260M |
| | Supported Living Framework | Dudley | £257M |
| | Lifts and Mobility Lift Solutions Framework | Alfreton | £250M |
| | Marine Gas Turbines - UK1 Pipeline Notice | Bristol | £250M |
| | National CPD/Workforce Education Framework (Non Apprenticeship) Mandatory May 2025 Update | Salisbury | £250M |
| | Building Repair and Maintenance 2026_cas-01062-Z8X5F5 | Devizes | £243M |
| | Adult Residential Care Homes | Hull | £240M |
| | Transportation and Infrastructure Professional Services Framework | Birmingham | £240M |
| | WESTCharge - Electric Vehicle Charging Infrastructure | Bristol | £240M |
| | Independent Alternative Provision (IAP) | Chichester | £225M |
| | Space Enabled and Geospatial Services Extension Notice | Liverpool | £216M |
| | Technology Group Strategic Partner - Customer Software Delivery - Customer Enablement - Re-Procurement | Darlington | £216M |
| | Rehabilitative Services for Women in Prison or the Community | London | £209M |
| | UK1 - Pipeline Notice - Personal Hard Armour Framework | Bristol | £208M |
| | Mainstream, SEN, and Local Bus Services Transport | Northallerton | £208M |
| | NHS NOFE and Midlands & East Branded Medicines - Tranche A- September | London | £207M |
| | NHS Scotland Business Systems Technology & Systems Integration Services | Edinburgh | £206M |
| | NHS Generic Pharmaceuticals - Wave 16b | London | £206M |
| | Care and Support Framework, Mental Health & Learning Disabiility | Bournemouth | £200M |