| | Personal Protective Equipment | Belfast | £5B |
| | Construction Professional Services 2 | Liverpool | £4B |
| | East Suffolk and North Essex NHS Foundation Trust - Acute Services | Ipswich | £2B |
| | East Suffolk and North Essex NHS Foundation Trust - Acute Services | Ipswich | £2B |
| | East Suffolk and North Essex NHS Foundation Trust - Acute Services | Ipswich | £2B |
| | East Suffolk and North Essex NHS Foundation Trust - Acute Services | Ipswich | £2B |
| | East Suffolk and North Essex NHS Foundation Trust - Acute Services | Ipswich | £2B |
| | East Suffolk and North Essex NHS Foundation Trust - Acute Services | Ipswich | £2B |
| | HMRC Enterprise Customer Relationship Management | London | £1B |
| | NOE CPC Total Technology Solutions II | Sheffield | £1B |
| | Project Reach | London | £935M |
| | Teachers and Temporary Staff (STaTS) 2 | Liverpool | £650M |
| | Flexible Purchasing Framework for Social Care Supports | Glasgow | £600M |
| | Owner's Engineer | London | £600M |
| | Prison Operator Services - HMP Oakwood | London | £600M |
| | Prison Operator Services HMP Oakwood | London | £600M |
| | NBC Science Hub Buildings (Main Works Contractor) - B951 | London | £511M |
| | Extension to Dynamic Purchasing System for Small Works | Harrogate | £500M |
| | Strategic Alliance | Devizes | £495M |
| | Housing Repairs & Maintenance Works and Services | Milton Keynes | £475M |
| | NBC Science Hub Buildings (Main Works Contractor) - B950 | London | £408M |
| | Concrete Sleepers (Doncaster) | London | £400M |
| | Total Fleet Solution Framework | Watford Hertfordshire | £400M |
| | Global System for Mobile Communications - Railway (GSM-R) Long Term Support (2G Transport Kontron) Framework | London | £378M |
| | Offshore Support Vessels | Bristol | £330M |
| | Light Touch for Home Care Support Services | Doncaster | £326M |
| | NHS London & South of England Branded Medicines - Tranche B | London | £315M |
| | Road Haulage and Warehousing Services | London | £308M |
| | DWP Digital Channels Contact Centre (DC3) | London | £265M |
| | Indirect Infrastructure Materials and Consumables | London | £250M |
| | Total Facilities Management | Leicester | £250M |
| | Railway Ballast & Aggregates | London | £240M |
| | Renewal of the North Wales Domiciliary Care Agreement | Ruthin | £240M |
| | East London NHS Foundation Trust - Mental Health Services 24/25 | London | £226M |
| | DWP Digital Channels Contact Centre (DC3) | London | £221M |
| | NHS NOFE and Midlands & East Branded Medicines - Tranche A- September | London | £207M |
| | DragonFire Minimum Deployable Capability 2 | London | £200M |
| | CF-Suction Consumables, Wound Drainage, Autologous Blood Systems and Related Accessories | London | £188M |
| | DDaT Data Centre (DC) Infrastructure Services - Preliminary Market Enagement Notice | London | £185M |
| | DDaT Data Centre (DC) Infrastructure Services - Preliminary Market Engagement Notice | London | £185M |
| | Digital Decision Accelerators for Defence (DDAD) Open Framework | Corsham | £180M |
| | Capital Works (Construction) Framework 2025 | Carlisle | £175M |
| | Home Care 2025 - Closed Framework | Beverley | £170M |
| | Replacement for Consultancy & Skilled Persons Framework | London | £170M |
| | Royal Free London NHS Foundation Trust Renal Dialysis Service Managed Service Agreement | London | £169M |
| | Integrated Community Musculoskeletal and Pain Service | Basildon | £164M |
| | Construction Works Framework | North Shields | £160M |
| | Permanent and Temporary Modular Buildings | Uxbridge | £155M |
| | General Construction and Marine Construction Frameworks | Liverpool | £150M |
| | Sterile Services and Endoscopy Decontamination Facility Solutions Framework | Chester | £150M |
| | Cables and Wires | London | £147M |
| | Defence IT Service Desk - UK1 - Pipeline Notice | Corsham | £140M |
| | Agency Workers - Non-Medical | Belfast | £135M |
| | Non-Emergency Patient Transport Service for Kent & Medway | Maidstone | £133M |
| | Fire Risk Assessment Remedial Works | Bradford | £133M |
| | NHS SBS Security Services, CCTV, and VSS Framework | Hemel Hempstead | £125M |
| | UMAL Insurance Broker | London | £125M |
| | London Construction Programme Consultancy Framework | London | £120M |
| | Suction Consumables, Wound Drainage, Autologous Blood Systems and Related Accessories | London | £120M |
| | Support Services for the Type 31 Combat Management System - UK1 | Bristol | £116M |
| | Design and Build Regina Road Combined With Demolition | Croydon | £100M |
| | IMS & POC Scanning System and Associated Hardware Devices | London | £100M |
| | Home Support - Principal Provider South Norfolk | Norwich | £93M |
| | Project Title: NHS National Framework for Golimumab Injection Commencing 1st November | London | £90M |
| | Southend Day Surgery Unit Managed Services Operator | Basildon | £85M |
| | Kirklees 0-19 Healthy Child Programme | Huddersfield | £84M |
| | NHS National Framework for Transition Products (Axitinib and Eltrombopag) | Leeds | £81M |
| | Nottinghamshire Healthy Families Programme | Nottinghamshire | £81M |
| | Microscopy & Imaging Equipment | Stirling | £80M |
| | Security and Cleaning Services | London | £80M |
| | London Liaison & Diversion Service and Mental Health Treatment Requirement (MHTR) Service for Men | Leeds | £79M |
| | Delivery Partnership Framework (DPF2) | Exeter | £75M |
| | Housing Planned Works (Scotland) Framework | Stirling | £75M |
| | Medical and Industrial Gases (Including Cylinders and Bulk Liquid Oxygen) | Hemel Hempstead | £70M |
| | Live-in Care (All-Ages), Complex Care (All-Ages) and Trusted Assessors for Spot Therapy and Clinical Psychology Provision… | Exeter | £61M |
| | NHS National Proprietary Pharmaceuticals - Low Molecular Weight Heparins - March | London | £61M |
| | ENHT, PAHT, WHHT - Minor Works Framework | Watford | £60M |
| | Parking and Traffic Enforcement & Associated Services | Catford | £60M |
| | Public Health Service in Sunderland (PSR Process C - Notice of Intention to Make an to… | Sunderland | £56M |
| | Freshly Prepared Sandwiches, Wraps, Paninis and Salads | Haslingden | £50M |
| | Social Housing | Newcastle | £50M |
| | Hard FM - Repairs and Maintenance Framework | Leicester | £50M |
| | DfI TRAM T-1145 Framework Surfacing Framework A | Belfast | £48M |
| | Aviation Support to British Army Training Unit Kenya | Andover | £45M |
| | Manned Guarding and Soft FM Security Services | Stockport | £45M |
| | 0-19 Services | Torquay | £42M |
| | Debt Management System | London | £40M |
| | Future Debt Solution | London | £40M |
| | Hector 2 | Raf High Wycombe | £40M |
| | Leisure Services and Management | London | £39M |
| | Demand Management & Renewables DPS - Technical Assistance Facility 2 | London | £39M |
| | Geosynthetics | London | £38M |
| | Cash Counter Payment Service to Residents Across Derbyshire | Matlock | £38M |
| | Younger Adults Extra Care Supported Living Services | Winchester | £38M |
| | Legal Services PA23 | London | £38M |
| | Live Music Event Producer R1BW & R2itP | London | £38M |
| | Retail and Event Catering Services at Imperial War Museums (IWM) | London | £37M |
| | Heavy Goods Vehicles (HGV) and Associated Trailers | Warrington | £36M |
| | Cleaning Consumables | Stockport | £35M |
| | Navy Base, Thermal, Outer Layer and Beanie Hat | Bristol | £34M |